Halazone 是一种非典型的抗菌磺酰胺衍生物,是碳酸酐酶 II (carbonic anhydrase II) 抑制剂,Kd 值为 1.45 ?M。Halazone 可保护钠通道免于灭活。Halazone 被广泛用于饮用水消毒。
货号:ajcx17310
CAS:80-13-7
分子式:C7H5Cl2NO4S
分子量:270.09
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 ?M. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].
[1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.