DBCO-amine 是一种可降解 (cleavable) 的 ADC linker,用于抗体偶联药物 (ADCs) 的合成。
货号:ajcx35472
CAS:1255942-06-3
分子式:C18H16N2O
分子量:276.33
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货
Background:
DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.