H3B-120 是一种高选择性，竞争性和变构的氨基甲酰磷酸合成酶 1 (CPS1) 抑制剂，IC50 为 1.5 μM，Ki 为 1.4 μM。H3B-120 具有抗癌活性。
货号:ajcx17030
CAS:2194903-42-7
分子式:C19H24N4O2S
分子量：372.48
溶解度:DMSO: 62.5 mg/mL (167.79 mM)
纯度：98%
存储：Store at -20°C
库存： 现货

Background:

H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity[1].

[1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.