Description:Prazosin 2HCl (formerly also known as cp-12299-1; Minipress, Peripress, Prazosin) is a potent and competitive alpha-1 adrenoceptor antagonist used to treat high blood pressure or benign prostatic hyperplasia, heart failure, hypertension, pheochromocytoma, Raynaud disease, prostratic hypertrophy and urinary retention. Prazosin leads to a significant increase in VEGF concentration in endothelial cells and angiogenesis only if eNOS is present. Prazosin binds to the α1-adrenergic receptors that are present on smooth muscle cells surrounding all larger blood vessels.
References:Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2300-8; Psychopharmacology (Berl). 2011 Nov;218(1): 89-99.
Related CAS#:19216-56-9 (free)
纯度:≥98%