GSK1940029是一种有效的酰基-辅酶A去饱和酶(SCD)抑制剂,详细信息请参考专利WO/2009060053A1中的化合物example16。
CAS:1150701-66-8
分子式:C18H16Cl2N4O2
分子量:391.25
纯度:98%
存储:Store at -20°C
Background:
GSK1940029 is a stearoyl-coa desaturase (SCD) extracted from patent WO/2009060053 A1, compound example 16.
GSK1940029 is a stearoyl-coa desaturase (SCD), which can be used to treat and/or preventing various diseases, including those mediated by SCD enzyme, such as diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, skin disorders such as acne, diseases or conditions related to cancer and the treatment of symptoms linked to the production of the amyloid plaque-forming Aβ42 peptide such as Alzheimer’s disease[1].
[1]. Anne Marie Jeanne Bouillot, et al. 1, 2, 3-triazole derivatives for use as stearoyl-coa desaturase inhibitors . PCT Int. Appl. (2009), WO 2009060053 A1 20090514.