Lofexidine 是选择性的、 α2 受体 激动剂,常用于缓解海洛因和其他阿片类戒断的躯体症状。
CAS:31036-80-3
分子式:C11H12Cl2N2O
分子量:259.13
纯度:98%
存储:Store at -20°C
Background:
Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2]. α2-receptor[1][2].
[1]. Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9(11):1371-7. [2]. Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44(2):343-51.