C8 dihydro Ceramide is a sphingolipid and an intermediate in the synthesis of C8 ceramide.
CAS:145774-33-0
分子式:C26H53NO3
分子量:427.7
纯度:98%
存储:Store at -20°C
Background:
C8 dihydro Ceramide is a sphingolipid and an intermediate in the synthesis of C8 ceramide . It is synthesized by the acylation of sphinganine by ceramide synthase, a process that can be inhibited by some fungal mycotoxins, such as fumonisin B1 . C8 dihydro Ceramide can be converted to C8 ceramide via the introduction of a 4,5-trans double bond by dihydroceramide desaturase. C8 dihydro ceramide is metabolically inactive and has been used as a negative control for the biological activity of C8 ceramide.