Thymosinbeta4是活细胞中actin聚合的有效调节剂。
CAS：77591-33-4
分子式：C212H350N56O78S
分子量：4963.44
纯度：98%
存储：Store at -20°C

Background:

Thymosin beta 4 is a potent regulator of actin polymerization in living cells.

As indicated by the significant reduction in the binding offluorescent phalloidin to injected cells, it is clear that (Thymosin beta 4 can induce an extensive depolymerization of actin filaments[1]. Treatment with the exogenous Thymosin beta 4 peptide inhibits the proliferation and migration of activated HSCs and reduces liver fibrosis[2].

[1]. Sanders MC, et al. Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4678-82. [2]. Kim J et al. Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells. Vitam Horm. 2016;102:121-49.