(S)-GNE-140是活性较小的GNE-140的对映体,能够抑制乳酸脱氢酶A(LDHA)。
CAS:2003234-64-6
分子式:C25H23ClN2O3S2
分子量:499.04
纯度:98%
存储:Store at -20°C
Background:
(S)-GNE-140 is the less active enantiomer of GNE-140 which can inhibit Lactate dehydrogenase A (LDHA).
[1]. Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7(10):896-901.