Nucleoside-Analog-1是抗病毒核苷R1479的类似物,用于HCV看病毒核苷类似物的合成。
CAS:876707-99-2
分子式:C9H9N5O5
分子量:267.2
纯度:98%
存储:Store at -20°C
Background:
Nucleoside-Analog-1 is a 4′-Azidocytidine analogue against Hepatitis C virus replication.
[1]. Smith DB, et al. The design, synthesis, and antiviral activity of 4’-azidocytidine analogues against hepatitis C virus replication: the discovery of 4’-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23. [2]. Smith DB, et al. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4’-azidocytidine against hepatitis C virus replication: the discovery of 4’-azido-2’-deoxy-2’-fluorocytidine and 4’-azido-2’-dideoxy-2’,2’-difluorocytidine. J Med Chem. 2009 May 14;52(9):2971-8.