HAEGTFTSDVS是GLP-1多肽N-端的1-11残基。
CAS：864915-61-7
分子式：C48H71N13O20
分子量：1150.18
纯度：98%
存储：Store at -20°C

Background:

HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.

The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2].

[1]. US20120264685 [2]. US9738697