Second-cephalosporin type antibiotic
CAS：121123-17-9
分子式：C18H21N3O6S
分子量：407.44
纯度：98%
存储：Store at -20°C

Background:

Cefprozil monohydrate (BMY-28100) is an orally administered cephalosporin and second-cephalosporin type antibiotic [1].

Cefprozil monohydrate has been reported to resistant to hydrolysis by the beta-lactmases. In addition, Cefprozil monohydrate has been found to be more active than either of the other agents against methicillin-susceptible strains of Staphylococcus aureus and S. epidermidis and all streptococci. For example, the MIC90 values are ≥16μg/ml,1.0μg/ml, 4μg/ml and＞128μg/ml for enterococci, Staphylococcus aureus (methicillin susceptible), Listeria monocytogenes and JK corynebacteria, respectively. Apart from these, Cefprozil monohydrate has been revealed to inhibit both β-lactamase-producing and β-lactamase-negative strains of H. influenzae with the MIC value of ranging from 2 to16μg/ml [1].

参考文献:
[1] Eliopoulos GM, Reiszner E, Wennersten C, Moellering RC Jr. In vitro activity of BMY-28100, a new oral cephalosporin. Antimicrob Agents Chemother. 1987 Apr;31(4):653-6.