C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase.
CAS:111122-57-7
分子式:C28H55NO3
分子量:453.7
纯度:98%
存储:Store at -20°C
Background:
C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 μM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner.