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Cremophor EL
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO: 61791-12-6
包装: 100mL
规格: 98%
市场价: 712元

半岛bd体育手机客户端 介绍
CremophorEL是一种聚乙氧基化表面活性剂。
CAS:61791-12-6
分子量:
纯度:98%
存储:Store at -20°C

Background:

Cremophor EL is a polyethoxylated surfactant.


Cremophor EL is a widely used excipient. In the first 10 h, Cremophor EL at 5 mg/mL increases the impedance, then decreases it, and after 20 h of treatment, epithelial cell death is detected. Cremophor EL decreases cell viability and increases cell toxicity more than RH40. Both epithelial viability and monolayer integrity are seriously impaired at 10 to 50 mg/mL concentrations of Cremophor EL at 24-h treatment. Cremophor EL also enhances cell detachment[1].



[1]. Kiss L, et al. Kinetic analysis of the toxicity of pharmaceutical excipients Cremophor EL and RH40 on endothelial and epithelial cells. J Pharm Sci. 2013 Apr;102(4):1173-81.


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