生物活性
BAY 61-3606是一种细胞可渗透的咪唑并嘧啶化合物，可作为Syk酪氨酸激酶活性的有效，ATP竞争性，可逆和高度选择性抑制剂，而对Btk，Fyn，Itk，Lyn和Src无抑制作用。
化学数据
| 目录号 |
A11320 |
| 作用机制 |
Inhibitor (抑制剂) |
| M. Wt |
390.4 |
| Formula |
C20H18N6O3 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
732983-37-8 |
| Synonyms |
BAY61-3606, BAY-61-3606 |
| SMILES |
COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC |
储备液配制
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
25.61 mL |
128.07 mL |
256.15 mL |
| 0.5 mM |
5.12 mL |
25.61 mL |
51.23 mL |
| 1 mM |
2.56 mL |
12.81 mL |
25.61 mL |
| 5 mM |
0.51 mL |
2.56 mL |
5.12 mL |
*The above data is based on the productmolecular weight 390.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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