ML400 is an allosteric inhibitor of LMPTP. ML400. ML400 is potent (EC50~1μM), selective against other phosphatases, and exhibits good cell-based activity as well as rodent pharmacokinetics. As such it should be a valuable tool to explore the effects of selective LMPTP inhibition in vitro and in vivo. References: Ardecky RJ, Hedrick MP, Stanford SM, Bliss MR, Zou J, Gosalia P, Yamamoto F, Milewski M, Barron N, Sun Q, Ganji S, Mehta A, Sugarman E, Nguyen K, Vasile S, Suyama E, Mangravita-Novo A, Salaniwal S, Kung P, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Bottini N. Allosteric Small Molecule Inhibitors of LMPTP. 2014 Apr 15 [updated 2015 Jan 16]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-. Available from .gov/books/NBK280042/ PubMed PMID: 25834896.

纯度：≥98%

CAS：1908414-42-5