生物活性

Riluzole (Rilutek)阻断与受损神经元有关的TTX敏感性钠通道，从而减少钙离子的流入并间接防止谷氨酸受体的刺激。

靶点信息

Sodium channel	NMDA receptor	Glutamate release

化学数据

目录号	A10795
M. Wt	234.2
Formula	C8H5F3N2OS
Purity	>99%
Storage	Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1744-22-5
Synonyms	PK-26124, RP-54274, Rilutek
SMILES	C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N

溶解度

In vitro	DMSO	42 mg/mL (179.33 mM)
	Water	Insoluble
	Ethanol	42 mg/mL (179.33 mM)
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	42.7 mL	213.49 mL	426.99 mL
0.5 mM	8.54 mL	42.7 mL	85.4 mL
1 mM	4.27 mL	21.35 mL	42.7 mL
5 mM	0.85 mL	4.27 mL	8.54 mL

*The above data is based on the productmolecular weight 234.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.