生物活性

NXY-059是具有自由基捕获特性的神经保护性自旋捕集器苯基丁腈或“ PBN”的二磺酰基衍生物。它大大减轻了灵长类动物脑缺血引起的功能障碍。

靶点信息

化学数据

目录号	A10663
M. Wt	381.3
Formula	C11H13NNa2O7S2
Purity	>99%
Storage	Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	168021-79-2
Synonyms	NXY059, Disufenton sodium
SMILES	CC(C)(C)/[N+](=C/C1=C(C=C(C=C1)S(=O)(=O)[O-])S(=O)(=O)[O-])/[O-].[Na+].[Na+]

溶解度

In vitro (25°C)	DMSO	71 mg/mL (186.19 mM)
	Water	71 mg/mL (186.19 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.23 mL	131.13 mL	262.26 mL
0.5 mM	5.25 mL	26.23 mL	52.45 mL
1 mM	2.62 mL	13.11 mL	26.23 mL
5 mM	0.52 mL	2.62 mL	5.25 mL

*The above data is based on the productmolecular weight 381.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.