生物活性

Granisetron Hydrochloride是血清素5-ht3受体拮抗剂。

靶点信息

5-HT3

化学数据

目录号	A10437
作用机制	Antagonist (拮抗剂)
M. Wt	348.87
Formula	C18H24N4O.HCl
Purity	>99%
Storage	Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	107007-99-8
Synonyms	Kytril
SMILES	CN1C2CCCC1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C.Cl

溶解度

In vitro	DMSO	1 mg/mL (2.86 mM)
	Water	67 mg/mL (192.05 mM)
	Ethanol	1 mg/mL (2.86 mM)
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.66 mL	143.32 mL	286.64 mL
0.5 mM	5.73 mL	28.66 mL	57.33 mL
1 mM	2.87 mL	14.33 mL	28.66 mL
5 mM	0.57 mL	2.87 mL	5.73 mL

*The above data is based on the productmolecular weight 348.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.