生物活性

Flucytosine是一种抗真菌药，用于治疗严重念珠菌和隐球菌感染。它进入真菌后转化为氟尿嘧啶，抑制DNA和RNA合成。

靶点信息

化学数据

目录号	A10394
M. Wt	129.1
Formula	C4H4FN3O
Purity	>99%
Storage	Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2022-85-7
Synonyms	5-fluorocytosine, Ancotil
SMILES	C1=NC(=O)NC(=C1F)N

溶解度

In vitro (25°C)	DMSO	7 mg/mL (54.22 mM)
	Water	4 mg/mL (30.98 mM)
	Ethanol	Insoluble
In vivo	0.5% methylcellulose+0.2% Tween 80	4 mg/mL
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	77.46 mL	387.3 mL	774.59 mL
0.5 mM	15.49 mL	77.46 mL	154.92 mL
1 mM	7.75 mL	38.73 mL	77.46 mL
5 mM	1.55 mL	7.75 mL	15.49 mL

*The above data is based on the productmolecular weight 129.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.