生物活性
Busulfan (Myleran,Busulfex)是烷基磺酸盐类中的细胞周期非特异性烷基化抗肿瘤药。
靶点信息
化学数据
目录号 |
A10169 |
M. Wt |
246.3 |
Formula |
C6H14O6S2 |
Purity |
>99% |
Storage |
Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. |
55-98-1 |
Synonyms |
Myleran, Busulfex, Busulphan |
SMILES |
CS(=O)(=O)OCCCCOS(=O)(=O)C |
溶解度
In vitro (25°C) |
DMSO |
43 mg/mL (174.58 mM) |
Water |
Insoluble |
Ethanol |
Insoluble |
In vivo |
2% DMSO+30% PEG 300+5% Tween 80+ddH2O |
4 mg/mL |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
0.1 mM |
40.6 mL |
203 mL |
406.01 mL |
0.5 mM |
8.12 mL |
40.6 mL |
81.2 mL |
1 mM |
4.06 mL |
20.3 mL |
40.6 mL |
5 mM |
0.81 mL |
4.06 mL |
8.12 mL |
*The above data is based on the productmolecular weight 246.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.