生物活性
JSH 23是NF-kB的抑制剂，可阻止其转运入细胞核（IC50 = 7.1 uM）。
化学数据
| 目录号 |
A14142 |
| 作用机制 |
Inhibitor (抑制剂) |
| M. Wt |
240.3 |
| Formula |
C16H20N2 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
749886-87-1 |
| Synonyms |
JSH-23,JSH23, NF??B Activation Inhibitor II |
| SMILES |
CC1=CC(=C(C=C1)NCCCC2=CC=CC=C2)N |
溶解度
| In vitro |
DMSO |
41 mg/mL (170.59 mM) |
| Water |
Insoluble |
| Ethanol |
17 mg/mL (70.73 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
41.61 mL |
208.07 mL |
416.15 mL |
| 0.5 mM |
8.32 mL |
41.61 mL |
83.23 mL |
| 1 mM |
4.16 mL |
20.81 mL |
41.61 mL |
| 5 mM |
0.83 mL |
4.16 mL |
8.32 mL |
*The above data is based on the productmolecular weight 240.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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