NU6300 is a covalent, irreversible (covalent), ATP-Competitive CDK2 inhibitor with Ki of 6 nM. References: Anscombe E, Meschini E, Mora-Vidal R, Martin MP, Staunton D, Geitmann M, Danielson UH, Stanley WA, Wang LZ, Reuillon T, Golding BT, Cano C, Newell DR, Noble ME, Wedge SR, Endicott JA, Griffin RJ. Identification and Characterization of an irreversible (covalent) Inhibitor of CDK2. Chem Biol. 2015 Sep 17;22(9):1159-64. doi: 10.1016/j.chembiol.2015.07.018. Epub 2015 Aug 27. PubMed PMID: 26320860; PubMed Central PMCID: PMC4579270.
纯度:≥98%
CAS:2070015-09-5