NUCC-555 is a first-in-class activin antagonist. It specifically binds to ALK4, which opens a completely new approach to inhibiting the activity of TGF-beta receptor superfamily members. References: Zhu J, Mishra RK, Schiltz GE, Makanji Y, Scheidt KA, Mazar AP, Woodruff TK. Virtual High-Throughput Screening To Identify Novel Activin Antagonists. J Med Chem. 2015 Jul 23;58(14):5637-48. doi: 10.1021/acs.jmedchem.5b00753. Epub 2015 Jul 7. PubMed PMID: 26098096; PubMed Central PMCID: PMC4635973.
纯度:≥98%
CAS:1060469-90-0