Aminocamptothecin (9-amino Camptothecin, 9-AC, 9-amino CPT), an analog of camptothecin (CPT) with higher water solubility, is a potent inhibitor of topoisomerase I with anti-tumor activity. It acts by disrupting the repair of single-strand DNA breakages. In human HT-29 colon adenocarcinoma, 9-AC showed high anti-proliferative activity/cytotoxicity with an IC50 value of 19 nM.

纯度：≥98%

CAS：91421-43-1