生物活性
TP-434 (Eravacycline)是一种新型的广谱氟环素抗生素，对表达主要抗生素抗性机制（包括四环素特异性外排和核糖体保护）的细菌具有活性。
化学数据
| 目录号 |
A13887 |
| M. Wt |
558.555 |
| Formula |
C27H31FN4O8 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
1207283-85-9 |
| Synonyms |
Eravacycline, TP434, TP 434 |
| SMILES |
CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=C(C(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)NC(=O)CN5CCCC5)F |
储备液配制
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
17.9 mL |
89.52 mL |
179.03 mL |
| 0.5 mM |
3.58 mL |
17.9 mL |
35.81 mL |
| 1 mM |
1.79 mL |
8.95 mL |
17.9 mL |
| 5 mM |
0.36 mL |
1.79 mL |
3.58 mL |
*The above data is based on the productmolecular weight 558.555. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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