生物活性
MDL-29951是在体外和体内均能激活NMDA受体的新型甘氨酸拮抗剂(Ki = 0.14 mM,[3H]甘氨酸结合)。
化学数据
目录号 |
A13729 |
作用机制 |
Antagonist (拮抗剂) |
M. Wt |
302.11 |
Formula |
C12H9Cl2NO4 |
Purity |
>99% |
Storage |
Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. |
130798-51-5 |
Synonyms |
MDL29951, MDL-29951 |
SMILES |
C1=C(C=C2C(=C1Cl)C(=C(N2)C(=O)O)CCC(=O)O)Cl |
储备液配制
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
0.1 mM |
33.1 mL |
165.5 mL |
331.01 mL |
0.5 mM |
6.62 mL |
33.1 mL |
66.2 mL |
1 mM |
3.31 mL |
16.55 mL |
33.1 mL |
5 mM |
0.66 mL |
3.31 mL |
6.62 mL |
*The above data is based on the productmolecular weight 302.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.