生物活性

TG003是Cdc2样激酶（Clk）的有效，特异性，可逆和ATP竞争性抑制剂。

靶点信息

CLK4	CLK1	CLK2
15 nM	20 nM	200 nM

化学数据

目录号	A13721
作用机制	Inhibitor (抑制剂)
M. Wt	249.3
Formula	C13H15NO2S
Purity	>99%
Storage	Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	300801-52-9
Synonyms	TG-003, TG-003
SMILES	CCN\1C2=C(C=CC(=C2)OC)S/C1=C\C(=O)C

溶解度

In vitro	DMSO	Warmed: 5 mg/mL (20.05 mM)
	Water	Insoluble
	Ethanol	Insoluble
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.11 mL	200.56 mL	401.12 mL
0.5 mM	8.02 mL	40.11 mL	80.22 mL
1 mM	4.01 mL	20.06 mL	40.11 mL
5 mM	0.8 mL	4.01 mL	8.02 mL

*The above data is based on the productmolecular weight 249.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.