Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.

1065755-99-8

C191H330N64O53S3

4467.29

Parstatin (human);Parstatin(human)

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years