Hydroxy-PEG6-Boc 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
半岛bd体育手机客户端 描述
Hydroxy-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
850090-09-4
分子式
C17H34O8
分子量
366.45
别名
1-羟基-3,6,9,12,15-五氧杂十八烷-18-羧酸叔丁酯;Hydroxy-PEG5-Boc
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years