Biotin-PEG4-ALKyne 是一种属于 PEG 类的、生物素标记的 PROTAC linker,可用于 PROTAC 分子的合成。
半岛bd体育手机客户端 描述
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
1458576-00-5
分子式
C21H35N3O6S
分子量
457.58
别名
生物素-四聚乙二醇-丙炔基;Biotin-PEG4-alkyne
储存和溶解度
DMSO:100 mg/mL (218.54 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years