BromperIDOl hydrochloride (R-11333 hydrochloride) 具有抗精神病活性,与中枢多巴胺受体 D2(Dopamine Receptors D2)具有高亲和力。BromperIDOl hydrochloride 与 Spectinomycin 可协同杀灭分枝杆菌 (mycobacteria)。
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描述
Bromperidol hydrochloride (R-11333 hydrochloride) possesses antipsychotic activity, with a high affinity for central dopamine receptors D 2. Bromperidol hydrochloride can kill mycobacteria in a synergistic manner with Spectinomycin [1] [2].
体内活性
Bromperidol hydrochloride antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats [1]. Bromperidol hydrochloride antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs [1].
Cas No.
59453-24-6
分子式
C21H24BrClFNO2
分子量
456.78
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years