Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

130209-78-8

C25H36O6

432.557

16-phenoxy tetranor Prostaglandin F2α isopropyl ester;16-phenoxy tetranor Prostaglandin F2α isopropyl ester

DMSO:100 mg/mL
PBS (pH 7.2):0.5 mg/mL
DMF:100 mg/mL
Ethanol:100 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years