B-Raf IN 8 (compound 7g) 是一种有效的B-Raf抑制剂，其IC50为 70.65 nM。B-Raf IN 8 对肝细胞癌 (HEPG-2)、结肠癌 (HCT-116)，乳腺癌 (MCF-7) 和人前列腺癌 (PC-3) 细胞表现出较强的抗肿瘤活性，IC50值分别为9.78、13.78、18.52 和 29.85 μM。

B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor, with an IC 50 of 70.65 nM. B-Raf IN 8 exhibits antitumor activity against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7) and human prostate cancer (PC-3) cells, with IC 50 values of 9.78, 13.78, 18.52 and 29.85 μM [1].

1215313-19-1

C18H17N3O2

307.35

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years