FAK-IN-3 (Compound 36) 是粘着斑激酶 (FAK) 的有效抑制剂。FAK-IN-3不仅降低了PA-1细胞的迁移和侵袭,还降低了MMP-2和MMP-9的表达。FAK-IN-3 抑制肿瘤生长和转移,无明显不良反应。FAK-IN-3 具有研究卵巢癌的潜力。
半岛bd体育手机客户端 描述
FAK-IN-3 (Compound 36) is a potent inhibitor of focal adhesion kinase ( FAK ). FAK-IN-3 not only decreases migration and invasion of PA-1 cells, but also reduces expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis, and no obvious adverse effects. FAK-IN-3 has the potential for the research of ovarian cancer [1].
分子式
C28H28N6O4
分子量
512.56
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years