CAII-IN-2 (compound 3g) 是一种硫代氨基脲衍生物,是一种有效的选择性碳酸酐酶-II (CA-II) 抑制剂,对牛 CA-II 的IC50值为 12.1 μM。CAII-IN-2 可用于碳酸酐酶相关生物疾病的研究。
半岛bd体育手机客户端 描述
CAII-IN-2 (compound 3g), a thiosemicarbazide derivative, is a potent, selective carbonic anhydrase-II (CA-II) inhibitor with an IC 50 value of 12.1 μM for bovine CA-II. CAII-IN-2 can be used in research of carbonic anhydrase related biological disorders [1].
体外活性
CAII-IN-2 (compound 3g) inhibits carbonic anhydrase-II (CA-II) by specifically mediate ionic interaction with the Zn ion in the active site of CA-II [1].
分子式
C18H19BrN4S
分子量
403.34
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years