GPVI antagonist 2 (Compound 1) 是 Glycoprotein VI (GPVI) 的潜在拮抗剂。GPVI antagonist 2 的IC50值分别为:胶原蛋白为 0.35 μM μM,CRP为 0.80 μM,convulxin为 195.2 μM,凝血酶为81.38 μM。糖蛋白 VI (GPVI) 是一种血小板主要胶原受体,是有效和安全的抗血栓研究的靶点。GPVI antagonist 2 是一种很有前途的抗血小板药物。
半岛bd体育手机客户端 描述
GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI ( GPVI ). IC 50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent [1].
Cas No.
880399-00-8
分子式
C24H27N3O4
分子量
421.49
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years