N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) 是由铜绿假单胞菌和洋葱状芽孢杆菌复合物菌株产生的细菌群体感应信号分子,群体感应是细菌用来控制基因表达以响应细胞密度增加的调节系统。N-3-oxo-dodecanoyl-L-Homoserine lactone诱导 16HBE 人支气管上皮细胞产生 IL-8。
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N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex [1] [2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. N-3-oxo-dodecanoyl-L-Homoserine lactone induces the IL-8 production in 16HBE human bronchial epithelial cells[3].
Cas No.
168982-69-2
分子式
C16H27NO4
分子量
297.39
别名
N-3-oxo-dodecanoyl-L-Homoserine lactone
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years