Mt KARI-IN-4 (compound 5c) 是一种有效的结核分歧杆菌酮醇酸还原异构酶 I (MtbKARI)抑制剂，Ki为 5.48 μM。Mt KARI-IN-4 对MtbH37Rv 具有抑制活性 (MIC = 0.78 μM)，且具有较低的细胞毒性 (HEK IC50>72 μg/mL)。

Mt KARI-IN-4 (compound 5c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase ( Mtb KARI) inhibitor with a K i value of 5.48 μM. Mt KARI-IN-4 has inhibitory activity against Mtb H37Rv (MIC = 0.78 μM) and low cytotoxicity (HEK IC 50 >72 μg/mL) [1].

2413974-53-3

C13H8FN5O3S2

365.36

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years