MTOB 是 c 末端结合蛋白 (CtBP) 的底物,可干扰 CtBP 在细胞培养物和小鼠中的致癌活性。它还积极调节 TCF-4 信号传导,导致癌症干细胞 (CSC) 生长和自我更新。
半岛bd体育手机客户端 描述
MTOB is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, leading to cancer stem cell (CSC) growth and self-renewal.
Cas No.
51828-97-8
分子式
C5H8NaO3S
分子量
171.17
别名
MTOB salt;4-甲硫基-2-氧丁酸钠;KMBA;α-keto-γ-Methylthiobutyric acid;4-methylthio 2-oxobutyric acid;MTOB
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years