SBP-3264是一种常用于研究急性髓性白血病中STK3和STK4左右价值的化学探针。
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SBP-3264 is a novel inhibitor of serine/threonine-protein kinases 3 and 4 (STK3 and STK4).
体外活性
SBP-3264 specifically inhibited the Hippo signaling pathway in cultured mammalian cells.
体内活性
SBP-3264 possessed favorable pharmacokinetic and pharmacodynamic properties in mice.
分子式
C19H20ClN5O
分子量
369.85
别名
SBP-3264
储存和溶解度
DMSO:60 mg/mL (162.23 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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