cis-Urocanic acid 是一种 5-HT2A 受体激动剂，cis-Urocanic acid 与 5-HT 受体结合的Kd 为 4.6 nM。cis-Urocanic acid 是一种免疫调节剂，通过与 5-HT2A 受体结合而诱导免疫抑制。

cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.

Treatment with 100 μg/mL cis-Urocanic acid completely suppresses IL-6 and IL-8 secretion decreases caspase-3 activity and improves cell viability against UV-B irradiation. No significant effects on IL-6 or IL-8 secretion, caspase-3 activity, or viability of the non-irradiated cells are observed with 100 μg/mL cis-Urocanic acid in both cell types [1].

7699-35-6

C6H6N2O2

138.12

(Z)-Imidazole-4-acrylic acid;(Z)-3-(1H-Imidazol-5-yl)acrylic acid;(E)-Urocanic acid;(Z)-Urocanic acid;cis-UCA;顺式-尿刊酸;cis-Urocanic acid

H2O:40 mg/mL (289.6 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years