Resibufogenin 是华蟾素的成分之一,表现出抑制氧化应激及肿瘤再生的活性。
半岛bd体育手机客户端 描述
1. Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .
Cas No.
465-39-4
分子式
C24H32O4
分子量
384.516
别名
酯蟾毒配基;酯蟾毒配基,蟾力苏;Bufogenin;Recibufogenin
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years