Tributyrin 是一种中性短链脂肪酸甘油三酯,是一种稳定且吸收迅速的丁酸前药。 它通过生物膜扩散并被细胞内脂肪酶代谢,在体内将有效的丁酸直接释放到细胞中,有抗增殖、促凋亡和诱导分化作用。
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Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent proapoptotic, antiproliferative, and differentiation-inducing effects.
Cas No.
60-01-5
分子式
C15H26O6
分子量
302.367
别名
NSC661583;甘油三丁酸酯;NSC 661583;NSC-661583
储存和溶解度
DMSO:100 mg/mL (330.73 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years