Chroman 1 dihydrochloride 是一种高效、选择性的ROCK抑制剂,对 ROCK2 (IC50=1 pM) 的作用比 ROCK1 (IC50=52 pM) 更强。Chroman 1 dihydrochloride 对MRCK也有抑制作用,其IC50值为 150 nM。
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Chroman 1 dihydrochloride is a highly potent and selective ROCK inhibitor. Chroman 1 dihydrochloride is more potent against ROCK2 ( IC 50 =1 pM) than ROCK1 ( IC 50 =52 pM). Chroman 1 dihydrochloride also has inhibitory activity against MRCK, with an IC 50 of 150 nM [1] [2].
分子式
C24H30Cl2N4O4
分子量
509.43
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years