Myrcene 是具有可挥发性的芳香族化合物,对 TNFα 诱导的 NF-Κb 具有抑制作用,且具有抗侵袭的能力。
半岛bd体育手机客户端 描述
Myrcene is a terpene that has been found in Cannabis and has antioxidative properties.
体内活性
Myrcene showed antioxidant activity and eliminated TCDD-induced oxidative stress in rats in a time-dependent manner.
动物实验
Rats (n = 112) were divided randomly into 8 equal groups. One group was kept as control and given corn oil as carrier. TCDD was orally administered at the dose of 2 μg/kg/week. Curcumin, myrcene and cineole were orally administered at the doses of 100 mg/kg/day, 200 mg/kg/day and 100 mg/kg/ day, respectively, by gavages dissolved in corn oil with and without TCDD. The liver samples were taken from half of all rats on day 30 and from the remaining half on day 60 for the determination of thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH), catalase (CAT), glutathione peroxidase (GSH-Px) and CuZn-SOD levels by spectrophotometric method. The results indicated that although TCDD significantly (p ≤ 0.01) increased formation of TBARS, it caused a significant decline in the levels of GSH, CAT, GSH-Px and CuZn-SOD in rats.
Cas No.
123-35-3
分子式
C10H16
分子量
136.238
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years