αvβ1 integrin-IN-1 TFA (Compound C8) is a highly potent and specific αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects. References: [1]. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Aug 30;7(10):902-907.
纯度:≥98%