(1R)-(-)-Myrtenal 是一种具有口服活性及抗肿瘤活性的萜烯。(-)-Myrtenal 作用于糖尿病大鼠的骨骼肌和肝脏,利用 Akt 增强 GLUT2 ,进而改善高血糖症。
半岛bd体育手机客户端
描述
(1R)-( )-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
体内活性
Diabetic rats were administered myrtenal (80 mg/kg bw) for a period of 28 days. Diabetic rats showed an increased the levels of plasma glucose, decreased the levels of plasma insulin, down-regulation of insulin receptor substrate 2 (IRS2), Akt and glucose transporter 2 (GLUT2) in liver and insulin receptor substrate 2 (IRS2), Akt and glucose transporter 4 (GLUT4) protein expression in skeletal muscle[1].
Cas No.
18486-69-6
分子式
C10H14O
分子量
150.22
别名
(1R)-(-)-桃金娘烯醛;桃金娘烯醛;(1R)-(–)-Myrtenal
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years