ML188是一种选择性非共价 SARS-CoV3CLpro抑制剂,具有抗病毒活性,IC50为 1.5 μM。
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ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
体外活性
Probe 16-(R) (ML188) is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action[1].
Cas No.
1417700-13-0
分子式
C26H31N3O3
分子量
433.552
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years