Ibotenic acid 对 N-甲基-D-天冬氨酸 (NMDA) 和反式-ACPD 或代谢型使君子氨酸 (Qm) 受体位点具有激动剂活性。
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描述
Ibotenic acid has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors.
体外活性
Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3 μM as measured by the release of lactate dehydrogenase to the culture media[1].
Cas No.
2552-55-8
分子式
C5H6N2O4
分子量
158.11
别名
Ibotenate;(+/-)-Ibotenic acid;DL-Ibotenic acid;(RS)-Ibotenic acid;鹅膏氨酸
储存和溶解度
DMSO:5 mg/mL (31.62 mM),Need ultrasonic
H2O:5 mg/mL (31.62 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years